Perilla Seed Extract (PSE) has been used in Japan & China by those with asthma and allergy & has been clinically tested in vitro & in vivo.
PSE inhibits the production of allergic mediators (Leukotrienes), that selectively inhibits 5-lipoxygenase activity and inhibits histamine release from mast cells.
PSE used daily reduces serum Ige levels. When PSE is discontinued, levels rise within 2 weeks.
PSE exhibits activity of 5-Lipoxygenase, Serum IgE, and TPA, thus inhibition of allergy.
PSE contains phytonutrients & rich linolenate oils, including rosmanaric acid, luteolin, chrysoeriol, and apigenin.
Ingredients included to promote bioavailability, provide antioxidants, anti- inflammatory support, nutrient support, and synergistic factors.
This great new product from NHC is truly one of our greatest. Users can see results quickly. Just take the product for two weeks at a load dose and see the difference. This product has ingredients in it that have been tested orally for histamine inhibition, reduction of Ige levels and mediation of Leukotrienes. Additionally, we have added basic vitamin and mineral support, targeting those vitamins and minerals that support immune function and allergy sufferers. We also include herbs and other support ingredients to facilitate bioavailability and congestion relief; provide antioxidant, anti-inflammatory, respiratory, antibiotic, circulation, and energy support.
PSE, the primary ingredient, has also been tested for those with asthma and some may find relief with this product. It has been used for thousands of years in Traditional Chinese Medicine for descending phlegm. The seed contains over 50% lipids and have a high content of linoleic, linolenic and oleic acids, polyphenols, and the flavonols. The primary flavonols of PSE that effect allergy are the rosmanaric acid, luteolin, chrysoeriol, and apigenin. While there are other important phytonutrients in PSE, these are the four we will focus on here for purposes of explanation, starting with the ingredient that has the most effect on histamine inhibition and working down to the least (which is still effective).