HCG 5000IU


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What is Human Chorionic Gonadotropin (hCG) and How it Can Help Men?

  • HCG (human chorionic gonadotropin) is produced by the human placenta, a sterile product derived from the urine of pregnant females. Recombinant DNA formulas are produced by pharmaceutical companies and compounding pharmacies.
  • In men, HCG mimics LH from the pituitary to stimulate Leydig cells of testes to produce testosterone.
  • It can have an additive effect on testosterone replacement therapy’s ( TRT) ¬†increases in estradiol, hematocrit and/or acne
  • The normal lyophilized vial contains 5,000 or 11,000 units HCG by compounding pharmacies (commercial products cost 3X compounding). The vial is sent with bacteriostatic water for reconstitution.
  • Used by fertility specialists to induce ovulation to harvest eggs, and sperm production.
  • The latest data show that men on TRT + HCG were able to remain fertile. (TRT + 500 IU HCG every other day)
  • The usual dose of 350-500 IU two times a week for the prevention/reversal of testicular atrophy. No data have been published on this use.
  • Anecdotal effect on raising sex drive in men. No data.
  • HCG acts as a Leydig cell stimulator and cell volumizer. Testicles regain size but do not grow beyond baseline size.
  • Continuous testosterone can reduce fertility in over 50% of TRT users and testicular size by 10-30 %. HCG may reverse those two issues.
  • Noticeable testicular size reduction can be a more common complaint in men with smaller testicular size at baseline. It may not be important to some older men or men not worried about fertility.
  • HCG may be used in patients who have abused steroids for 6-8 weeks before c l omiphene to attempt to accelerate the natural¬†production of testosterone.
  • May be used in younger males as the sole method of testosterone treatment with secondary hypogonadism. All men respond differently to HCG’s ability to boost T production by testes. Expensive as monotherapy and frequently used with testosterone replacement since that combination may be more cost-effective in normalizing testosterone and fertility.
  • HCG may reactivate upstream hormones like pregnenolone and progesterone that are shut down by testosterone replacement therapy.
  • HCG may not work well in some men who have primary hypogonadism, i.e. dysfunction of the Leydig cells in the testes


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