Description
SR-9009 TOPICAL liquid WITH DMSO
1ML PER PUMP
100ML A BOTTLE
- SR9009 25MG PER ML
DMSO 20MG
[HTML] Rev-erbα agonist SR9009 protects against cerebral ischemic injury through mechanisms involving Nrf2 pathway
M Sheng, X Chen, Y Yu, Q Wu, J Kou… – Frontiers in …, 2023 – frontiersin.org
… by SR9009 protects against acute ischemic brain damage partly via Nrf2 pathway. Methods:
Adult mice were pretreated with SR9009 … Results: We confirmed that SR9009 activated Rev-…
Adult mice were pretreated with SR9009 … Results: We confirmed that SR9009 activated Rev-…
[HTML] Circadian regulation of pulmonary disease: the importance of timing
PS Cunningham, C Jackson, A Chakraborty… – Clinical …, 2023 – portlandpress.com
… human circadian oscillations are also discussed as these will be useful outcome measures
in future interventional human trials … improved bioavailability, SR9009 has shown potential in …
in future interventional human trials … improved bioavailability, SR9009 has shown potential in …
[HTML] Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization
… lung injury, and SR9009 treatment helped alleviate the injury … injury, the bleomycin SR9009
group showed a significantly … side effects need further investigation for the pre-clinical trial. …
group showed a significantly … side effects need further investigation for the pre-clinical trial. …
[HTML] REV-ERB activation as a novel pharmacological approach for treating inflammatory pain
S Makhija, JD Griffett, GB Veerakanellore… – Frontiers in …, 2023 – frontiersin.org
… decrease in NLRP3 staining in both the SR9009 and STL1267-treated cells as compard to
… We found that while 10 μM SR9009 significantly suppressed the secretion of this cytokine …
… We found that while 10 μM SR9009 significantly suppressed the secretion of this cytokine …
Intermittent fasting reverses age-and obesity-associated adipose fibrosis through circadian reprogramming of adipose precursor cells.
JH Lee, Y Patel, JLH Yeung, Q Zhang, L Pickel, X He… – 2023 – researchsquare.com
… Our current study demonstrated that SR9009 treatment decreased α-SMA levels in murine
and human … In alignment with this finding, in vivo SR9009 treatment significantly reduced the …
and human … In alignment with this finding, in vivo SR9009 treatment significantly reduced the …
NR1D1 stimulates antitumor immune responses in breast cancer by activating cGAS-STING signaling
NL Ka, MK Park, SS Kim, Y Jeon, S Hwang, SM Kim… – Cancer Research, 2023 – AACR
… activation of NR1D1 by SR9009 exerts cytotoxic effects on a variety of … of SR9009 on tumor
growth in MMTV-PyMT model, mice were administrated with vehicle or 100 mg/kg SR9009 for …
growth in MMTV-PyMT model, mice were administrated with vehicle or 100 mg/kg SR9009 for …
Chronotherapy in dentistry: A scoping review
M Abusamak, M Al-Tamimi, H Al-Waeli… – Chronobiology …, 2023 – Taylor & Francis
… JBI critical appraisal tools were used in this study because JBI’s checklists have the
widest applicable range for human studies (eg Randomized Controlled Trials (RCTs), non-RCTs, …
widest applicable range for human studies (eg Randomized Controlled Trials (RCTs), non-RCTs, …
Intestinal clock modulates rhythmic hepatic metabolism
MF Fondevila, B Schnabl – Journal of Hepatology, 2023 – journal-of-hepatology.eu
… The authors used SR9009, a REV-ERBα agonist, and SR8278, a REV-ERBα antagonist,
with poor oral bioavailability. Oral administration of SR9009 lowered plasma lipid profile and …
with poor oral bioavailability. Oral administration of SR9009 lowered plasma lipid profile and …
[HTML] The Role of REV-ERB Receptors in Cancer Pathogenesis
G Gomatou, A Karachaliou, OZ Veloudiou… – International Journal of …, 2023 – mdpi.com
… The treatment with the small-molecule agonists of REV-ERBs SR9011 and SR9009 led to
a reduction in the GSC proliferation rate 51. Noteworthily, the combination of SR9011 with …
a reduction in the GSC proliferation rate 51. Noteworthily, the combination of SR9011 with …
[HTML] Brain nuclear receptors and cardiovascular function
M Wang, Y Yang, Y Xu – Cell & Bioscience, 2023 – cellandbioscience.biomedcentral …
Brain–heart interaction has raised up increasing attentions. Nuclear receptors (NRs) are
abundantly expressed in the brain, and emerging evidence indicates that a number of these …
abundantly expressed in the brain, and emerging evidence indicates that a number of these …
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