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S-23 is a selective androgen receptor modulator (SARM).1 It binds to the AR (Ki = 1.7 nM) and induces AR-mediated transcriptional activation in CV-1 cells expressing the human receptor when used at a concentration of 10 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. It decreases testicular sperm concentration without reducing mounting behavior or the number of intromissions in intact rats when administered in combination with estradiol benzoate (Item No. 10006487). S-23 (3 mg/kg) also increases preference for sexually active intact males when administered to ovariectomized female rats.2
80 in stock
Product Categories
PRODUCT TYPE
Biochemicals(13,481)
Receptor Pharmacology(1,832)
RESEARCH AREA
Metabolism(2,486)
Reproductive Biology(227)
Technical Information
Formal Name: (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-propanamide
CAS Number: 1010396-29-8
Molecular Formula: C18H13ClF4N2O3
Formula Weight: 416.8
Purity: ≥98%
Formulation
A solid
λmax
216, 271 nm
SMILES
O=C([C@](O)(C)COC1=CC(F)=C(Cl)C=C1)NC2=CC=C(C#N)C(C(F)(F)F)=C2
InChi Code: InChI=1S/C18H13ClF4N2O3/c1-17(27,9-28-12-4-5-14(19)15(20)7-12)16(26)25-11-3-2-10(8-24)13(6-11)18(21,22)23/h2-7,27H,9H2,1H3,(H,25,26)/t17-/m0/s1
InChi Key: SSFVOEAXHZGTRJ-KRWDZBQOSA-N
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US may vary elsewhere
Stability: ≥ 2 years
Product Description
S-23 is a selective androgen receptor modulator (SARM).1 It binds to the AR (Ki = 1.7 nM) and induces AR-mediated transcriptional activation in CV-1 cells expressing the human receptor when used at a concentration of 10 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. It decreases testicular sperm concentration without reducing mounting behavior or the number of intromissions in intact rats when administered in combination with estradiol benzoate (Item No. 10006487). S-23 (3 mg/kg) also increases preference for sexually active intact males when administered to ovariectomized female rats.2
WARNING This product is not for human or veterinary use.
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